Pancreatic adenocarcinoma: epidemiology and genetics.
نویسندگان
چکیده
منابع مشابه
Pancreatic adenocarcinoma: epidemiology and genetics.
Pancreatic adenocarcinoma is an important cause of death from cancer throughout the developed world. There are few established environmental risk factors, but a previous history of pancreatitis and exposure to tobacco and salted food appear to be the most important. A family history of pancreatic adenocarcinoma is not common in patients with this disease, but recent research has shown that panc...
متن کاملGenetics and Biology of Pancreatic Ductal Adenocarcinoma.
Pancreatic ductal adenocarcinoma remains a clinical challenge. Thus far, enlightenment on the downstream activities of Kras, the tumor's unique metabolic needs, and how the stroma and immune system affect it have remained untranslated to the clinical practice. Given the numbers of diverse therapies in development and a growing knowledge about how to evaluate these systems preclinically and clin...
متن کاملEpidemiology and genetics of pancreatic cancer
Pancreatic ductal adenocarcinoma (and its histological variants), also referred to as pancreatic cancer (PC) comprises 90% of exocrine pancreatic neoplasms [1]. This highly aggressive cancer is the fourth leading cause of cancer death in the USA [2]. More than 80% of patients with PC present with advanced disease that is incurable by surgery. Most tumors greater than 5 cm in size show dissemina...
متن کاملMolecular Genetics and Epidemiology of Vitiligo
Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...
متن کاملCharcot–Marie–Tooth disease: Genetics, epidemiology and complications
Background and aims: Charcot Marie Tooth disease (CMT) is the most prevalent hereditary neuropathy and its frequency is 1 in 2500. CMT is a heterogeneous disease and has different clinical symptoms. The prevalence of CMT and involved genes differ in different countries. CMT patients experience considerable sleep problems and a higher risk of decreased quality of life. In this w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1996
ISSN: 1468-6244
DOI: 10.1136/jmg.33.11.889